Much of the debate over the use of animal testing in drug development is a cocktail of facts, emotions and ethics. Regulators have tried to strike a balance between these factors in the forthcoming EU Directive 2010/63/EU, but there is still considerable pressure to stop animal testing altogether. What would happen to drug development, and where would it take place, if animal testing were banned? It’s difficult to find the ‘right’ answers, particularly when rare, or orphan, diseases are involved.
Orphan diseases, affect not more than 5 in 10000 people, With some 29 million sufferers in the EU;
Given my interest in issues around animal testing, these timely reminders of the burden of disease got me thinking about the contribution that research has made to human health.